Autoimmune Hemolytic Anemia after Intravenous Immunoglobulin Therapy in a Child with Kawasaki Disease / 임상소아혈액종양
Clinical Pediatric Hematology-Oncology
;
: 162-166, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-30884
ABSTRACT
Kawasaki disease (KD) can cause acquired heart disease and systemic vasculitis in children. It is treated with intravenous immunoglobulin (IVIG). A significant complication is development of coronary artery lesions such as dilatations or aneurysms. However, uncommon complications can occur, like autoimmune hemolytic anemia when IVIG is used. We present a case of autoimmune hemolytic anemia associated with KD. Dilatation of right coronary artery was found at echocardiography and he was treated twice with IVIG (2 g/kg) with interval of 48 hours. Laboratory finding showed hemoglobin 7.1 g/dL, hematocrit 20.8%, corrected reticulocyte 5.86%, total bilirubin 0.29 mg/dL, lactate dehydrogenase 425 IU/L, and haptoglobin 5 mg/dL. Normocytic, normochromic anemia with anisopoikilocytosis was found on peripheral blood smear, and direct antiglobulin test was positive. The patient was started on oral prednisolone for 3 weeks, with which all symptoms resolved. We report this rare case, prompting consideration of IVIG associated complications when treating KD.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Reticulócitos
/
Bilirrubina
/
Haptoglobinas
/
Imunoglobulinas
/
Teste de Coombs
/
Prednisolona
/
Ecocardiografia
/
Imunização Passiva
/
Imunoglobulinas Intravenosas
/
Vasos Coronários
Limite:
Criança
/
Humanos
Idioma:
Inglês
Revista:
Clinical Pediatric Hematology-Oncology
Ano de publicação:
2016
Tipo de documento:
Artigo
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