Preliminary study on immunosuppressive effects evaluation of biomaterial / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
;
(6): 20-22, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-309544
ABSTRACT
In this paper, an immunosuppression model of immunotoxicity built through applying immunosuppressive agent-cyclophosphamide. Subsequently the changes of some assessment indexes including total amount of lymphocytes and concentration of cytokine TNF-alpha in peripheral blood were observed and were used to evaluate immunotoxicity induced by Medical Heat Vulcanizing Silicone Rubber. The final results showed no immunosuppressive effect caused by this material. The study provide effective and sensitive detection technique for evaluation of medical devices and biomaterials' immunotoxicity.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Borracha
/
Silicones
/
Materiais Biocompatíveis
/
Sangue
/
Teste de Materiais
/
Linfócitos
/
Fator de Necrose Tumoral alfa
/
Elastômeros
/
Alergia e Imunologia
/
Toxicidade
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Medical Instrumentation
Ano de publicação:
2009
Tipo de documento:
Artigo
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