Isolation of Id1 interaction protein in human prostate cancer / 中华男科学杂志
National Journal of Andrology
;
(12): 796-799, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-309792
ABSTRACT
<p><b>OBJECTIVE</b>To isolate the inhibitor of DNA binding 1 (Id1) interaction protein and to determine the role and action mechanism of Id1 in human prostate cancer.</p><p><b>METHODS</b>The expression vector pET-28a/Id1 was established and used as a bait to prey the interaction protein by pull-down assay.</p><p><b>RESULTS</b>A clear interaction protein band was observed by SDS-PAGE, which was found to be activating transcription factor 3 (ATF3) by Western blotting.</p><p><b>CONCLUSION</b>Id1 may play a role in human prostate cancer by interacting with ATF3.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias da Próstata
/
RNA
/
Reação em Cadeia da Polimerase Via Transcriptase Reversa
/
Fator 3 Ativador da Transcrição
/
Proteína 1 Inibidora de Diferenciação
/
Genética
/
Metabolismo
Limite:
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2008
Tipo de documento:
Artigo
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