Relationship between alcohol consumption and risk factors for cardiovascular disease / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 89-94, 2009.
Article
em Zh
| WPRIM
| ID: wpr-310386
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the relationship between alcohol consumption and risk factors for cardiovascular disease.</p><p><b>METHODS</b>Two hundreds and twenty six subjects were enrolled in the study and grouped to non-drinkers, mild drinkers, moderate drinkers and heavy drinkers. Serum GGT, hs-CRP, %CDT, HCY, lipoprotein were measured in all groups.</p><p><b>RESULT</b>There were significantly higher GGT levels with heavy drinkers than those with other groups (P <0.05), and GGT levels were increased with increasing alcohol intake; and there were significantly higher %CDT levels with heavy drinkers compared with those with no-drinkers; there was significant higher hs-CRP levels with heavy drinkers compared with those with mild and moderate drinkers (P<0.05); but in moderate drinkers there was significantly lower hs-CRP levels than non drinkers (P<0.05). Compared with non-drinkers, there were significantly lower LDL-C and TG levels with mild and moderate drinkers. There were no significant differences in CHOL, HDL-C, HCY, WBC, MCV levels among all groups. Heavy drinkers had higher smoking rate and higher prevalence of hypertension (P <0.05).</p><p><b>CONCLUSION</b>Heavy alcohol consumption results in increasing GGT,%CDT and hs-CRP and may increase cardiovascular disease risk along with other risk factors.Mild to moderate alcohol consumption is associated with lower hs-CRP concentration,which may protect the cardiovascular system through anti-inflammatory mechanism.</p>
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Índice:
WPRIM
Assunto principal:
Sangue
/
Consumo de Bebidas Alcoólicas
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Proteína C-Reativa
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Transferrina
/
Doenças Cardiovasculares
/
China
/
Epidemiologia
/
Inquéritos e Questionários
/
Fatores de Risco
/
Alcoolismo
Tipo de estudo:
Etiology_studies
/
Risk_factors_studies
Limite:
Adolescent
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Adult
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Aged
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Humans
/
Male
País/Região como assunto:
Asia
Idioma:
Zh
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2009
Tipo de documento:
Article