Surface Modification of Intraocular Lenses / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 206-214, 2016.
Artigo
em Inglês
| WPRIM
| ID: wpr-310682
ABSTRACT
<p><b>OBJECTIVE</b>This paper aimed to review the current literature on the surface modification of intraocular lenses (IOLs).</p><p><b>DATA SOURCES</b>All articles about surface modification of IOLs published up to 2015 were identified through a literature search on both PubMed and ScienceDirect.</p><p><b>STUDY SELECTION</b>The articles on the surface modification of IOLs were included, but those on design modification and surface coating were excluded.</p><p><b>RESULTS</b>Technology of surface modification included plasma, ion beam, layer-by-layer self-assembly, ultraviolet radiation, and ozone. The main molecules introduced into IOLs surface were poly (ethylene glycol), polyhedral oligomeric silsesquioxane, 2-methacryloyloxyethyl phosphorylcholine, TiO 2 , heparin, F-heparin, titanium, titanium nitride, vinyl pyrrolidone, and inhibitors of cytokines. The surface modification either resulted in a more hydrophobic lens, a more hydrophilic lens, or a lens with a hydrophilic anterior and hydrophobic posterior surface. Advances in research regarding surface modification of IOLs had led to a better biocompatibility in both in vitro and animal experiments.</p><p><b>CONCLUSION</b>The surface modification is an efficient, convenient, economic and promising method to improve the biocompatibility of IOLs.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ozônio
/
Fosforilcolina
/
Raios Ultravioleta
/
Heparina
/
Química
/
Interações Hidrofóbicas e Hidrofílicas
/
Lentes Intraoculares
/
Metacrilatos
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2016
Tipo de documento:
Artigo
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