An investigation of the effects of curcumin on anxiety and depression in obese individuals: A randomized controlled trial / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 332-338, 2015.
Artigo
em Inglês
| WPRIM
| ID: wpr-310840
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the effectiveness of curcumin, a natural polyphenolic compound with antioxidant and anti-inflammatory activities, on the frequency of symptoms of anxiety and depression in obese individuals.</p><p><b>METHODS</b>In this double blind, cross-over trial, 30 obese subjects were randomized to receive either curcumin (1 g/day) or placebo for a period of 30 days. Following a wash-out interval of 2 weeks, each subject was crossed over to the alternative regimen for a further 30 days. Severity of anxiety and depression was assessed at baseline and at weeks 4, 6 and 10 of the trial using the Beck Anxiety Inventory (BAI) and Beck Depression Inventory (BDI) scales, respectively.</p><p><b>RESULTS</b>Mean BAI score was found to be significantly reduced following curcumin therapy (P=0.03). However, curcumin supplementation did not exert any significant impact on BDI scores (P=0.7).</p><p><b>CONCLUSION</b>Curcumin has a potential anti-anxiety effect in individuals with obesity.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ansiedade
/
Placebos
/
Escalas de Graduação Psiquiátrica
/
Demografia
/
Curcumina
/
Usos Terapêuticos
/
Depressão
/
Tratamento Farmacológico
/
Obesidade
Tipo de estudo:
Ensaio Clínico Controlado
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Chinese journal of integrative medicine
Ano de publicação:
2015
Tipo de documento:
Artigo
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