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Ginkgo Biloba extract for angina pectoris: a systematic review / 中国结合医学杂志
Chinese journal of integrative medicine ; (12): 542-550, 2015.
Artigo em Inglês | WPRIM | ID: wpr-310845
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of Ginkgo Biloba extract for patients with angina pectoris according to the available evidence.</p><p><b>METHODS</b>Electronic databases were searched for all of the randomized controlled trials (RCTs) of angina pectoris treatments with Ginkgo Biloba extract, either alone or combined with routine Western medicine (RWM), and controlled by untreated, placebo, Chinese patent medicine, or RWM treatment. The RCTs were retrieved from the following electronic databases PubMed/MEDLINE, ProQuest Health and Medical Complete, Springer, Elsevier, and ProQuest Dissertations and Theses, Wanfang Data, China National Knowledge Infrastructure (CNKI), VIP database, China Biology Medicine (CBM), Chinese Medical Citation Index (CMCI), from the earliest database records to December 2012. No language restriction was applied. Study selection, data extraction, quality assessment, and data analyses were conducted according to the Cochrane standards. RevMan 5.1.0 provided by Cochrane Collaboration The data were analysed by using.</p><p><b>RESULTS</b>A total of 23 RCTs (involving 2,529 patients) were included and the methodological quality was evaluated as generally low. Ginkgo Biloba extract with RWM was more effective in angina relief and electrocardiogram improvement than RWM alone. Reported adverse events included epigastric discomfort, nausea, gastrointestinal reaction, and bitter taste.</p><p><b>CONCLUSIONS</b>Ginkgo Biloba extract may have beneficial effects on patients with angina pectoris, although the low quality of existing trials makes it difficult to draw a satisfactory conclusion. More rigorous, high quality clinical trials are needed to provide conclusive evidence.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Volume Sistólico / Diagnóstico por Imagem / Extratos Vegetais / Débito Cardíaco / Química / Ensaios Clínicos como Assunto / Ultrassonografia / Ginkgo biloba / Usos Terapêuticos / Tratamento Farmacológico Tipo de estudo: Ensaio Clínico Controlado / Estudo diagnóstico / Guia de Prática Clínica / Revisões Sistemáticas Avaliadas Limite: Humanos Idioma: Inglês Revista: Chinese journal of integrative medicine Ano de publicação: 2015 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Volume Sistólico / Diagnóstico por Imagem / Extratos Vegetais / Débito Cardíaco / Química / Ensaios Clínicos como Assunto / Ultrassonografia / Ginkgo biloba / Usos Terapêuticos / Tratamento Farmacológico Tipo de estudo: Ensaio Clínico Controlado / Estudo diagnóstico / Guia de Prática Clínica / Revisões Sistemáticas Avaliadas Limite: Humanos Idioma: Inglês Revista: Chinese journal of integrative medicine Ano de publicação: 2015 Tipo de documento: Artigo