Study of 125I-interleukin-8 distribution in mice / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 95-96, 2003.
Article
em Zh
| WPRIM
| ID: wpr-311099
Biblioteca responsável:
WPRO
ABSTRACT
IL-8 was radiolabeled with 125I via Bolten-Hunter agent and the distribution of 125I-IL-8 in mice was determined in order to understand IL-8 behaviors in vivo. The percentage of 125I-IL-8 in blood, heart, liver, lung, kidneys, bone and spleen was obtained. The half-clearance of fast phase T1/2 alpha and slow phase T1/2 beta were 0.32 h and 8.01 h respectively. Most of 125I-IL-8 was excluded by kidneys.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Proteínas Recombinantes
/
Farmacocinética
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Distribuição Tecidual
/
Interleucina-8
/
Radioisótopos do Iodo
Limite:
Animals
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2003
Tipo de documento:
Article