The roles of VEGF and C-myc in occurrence, development and metastasis of gallbladder carcinoma / 生物医学工程学杂志
Journal of Biomedical Engineering
; (6): 68-70, 2003.
Article
em Zh
| WPRIM
| ID: wpr-311106
Biblioteca responsável:
WPRO
ABSTRACT
To investigate the relationship of the expression of vascular endothelial growth factor (VEGF) and C-myc with the occurrence, development and metastasis of gallbladder carcinoma, the expression levels of VEGF and C-myc in gallbladder carcinoma tissue (n = 30) and in normal gallbladder tissue (n = 20) were examined by immunochemistry. Results show that the positive rates of VEGF and C-myc in gallbladder carcinoma tissue were 80% and 63.3% respectively, and 45% and 25% respectively in normal gallbladder tissue. The positive rates of VEGF and C-myc were significantly higher in gallbladder carcinoma than in normal gallbladder tissue. The expression of VEGF and C-myc in gallbladder carcinoma related to the metastasis of gallbladder carcinoma. VEGF and C-myc play important roles in the occurrence, development and metastasis of gallbladder carcinoma.
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Índice:
WPRIM
Assunto principal:
Patologia
/
Fisiologia
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Fatores de Crescimento Endotelial
/
Proteínas Proto-Oncogênicas c-myc
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Linfocinas
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Peptídeos e Proteínas de Sinalização Intercelular
/
Fatores de Crescimento do Endotélio Vascular
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Fator A de Crescimento do Endotélio Vascular
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Neoplasias da Vesícula Biliar
/
Metabolismo
Limite:
Adult
/
Aged
/
Female
/
Humans
/
Male
Idioma:
Zh
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2003
Tipo de documento:
Article