Association of Dietary Pattern during Pregnancy and Gestational Diabetes Mellitus: A Prospective Cohort Study in Northern China / 生物医学与环境科学（英文）

ABSTRACT

<p><b>OBJECTIVE</b>To examine the association of maternal dietary patterns during pregnancy with gestational diabetes mellitus (GDM) in northern China.</p><p><b>METHODS</b>The dietary intakes of pregnant women were recorded twice by 24-hour dietary recalls for three days prior to having been diagnosed with GDM, at 5-15 and 24-28 gestational weeks, respectively. GDM was diagnosed, and serum glycosylated hemoglobin (HbA1c) was measured at 24-28 weeks. Dietary patterns were assessed by factor analysis. The association of the dietary pattern with GDM and HbA1c was examined by multiple logistic models.</p><p><b>RESULTS</b>Of 753 participants, 64 (8.5%) were diagnosed with GDM. Four dietary patterns were identified Western pattern (dairy, baked/fried food and white meat), traditional pattern (light-colored vegetables, fine grain, red meat and tubers), mixed pattern (edible fungi, shrimp/shellfish and red meat) and prudent pattern (dark-colored vegetables and deep-sea fish). Compared with the prudent pattern, both the Western pattern and the traditional pattern were associated with an increased risk of GDM (aOR = 4.40, 95% CI 1.58-12.22; aOR = 4.88, 95% CI 1.79-13.32) and a high level of HbA1c (aOR = 12.37, 95% CI 1.47-103.91; aOR = 26.23, 95% CI 2.54-270.74). Compared to the lowest quartile (Q), Q3 of the Western pattern scores and Q3-Q4 of the traditional pattern scores were associated with a higher risk of GDM.</p><p><b>CONCLUSION</b>The consumption of the Western pattern or the traditional pattern during pregnancy may increase the risk of GDM.</p>