Study on a new antarthritic injection--O-carboxymethyl chitosan / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 25-27, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-312874
ABSTRACT
A type of water-soluble carboxymethyl chitosan (O--CMC), with 76% degree of substitution determined by conductivity method, was prepared by using chloroacetic acid to react with C6-OH of chitosan. The solubility of O--CMC was characterized also. Animal experiment in rabbits showed that O--CMC could lubricate arthron, inhibit proliferation of fibroblast cells on rabbits' knee joints, benefit the process of repairing pathologic articular cartilage, and produce good therapeutic effect on rheumatoid arthritis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Artrite Experimental
/
Cartilagem Articular
/
Usos Terapêuticos
/
Quitosana
/
Proliferação de Células
/
Tratamento Farmacológico
/
Fibroblastos
/
Injeções Intra-Articulares
/
Articulação do Joelho
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2004
Tipo de documento:
Artigo
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