Relative Risk Factors of Prognosis in IgA Nephropathy Patients with Depressed Renal Functions / 대한신장학회지
Korean Journal of Nephrology
;
: 198-207, 2010.
Artigo
em Coreano
| WPRIM
| ID: wpr-31395
ABSTRACT
PURPOSE:
This study was aimed at finding clinical factors to be associated with a progressive course of IgA nephropathy.METHODS:
We investigated the association between the prognosis of IgA nephropathy and clinical and laboratory findings including age, sex, hypertension, diabetes mellitus, 24-hour urine protein, macroscopic hematuria, hematuria duration, serum uric acid, serum creatinine, GFR, upper respiratory infection, pathological observation, and treatment protocols. One hundred seventy seven patients were followed up for more than 2 years at Kyung Hee university medical center from January 1997 through December 2006. Kidney size and echogenicity were measured by abdominal ultrasonography. Resistive index was calculated by doppler ultrasonography.RESULTS:
Long hematuria duration, increased uric acid, elevated creatinine of chronic renal failure group were distinguished from those of normal and acute renal failure group statistically. Using multivariate analysis, three factors, elevated serum uric acid, decreased GFR, ACE inhibitor or ARB and steroid combination treatment proved to be independent prognostic indicators of acute renal failure of IgA nephropathy. Heavy proteinuria, long hematuria duration, and severe histopathologic findings by Haas' classification were associated with significant risk factors for developing chronic renal failure.CONCLUSION:
At diagnosis of IgA nephropathy, hematuria continuation and histological damage in Haas' classification were related with the reduction of renal function.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Prognóstico
/
Proteinúria
/
Ácido Úrico
/
Imunoglobulina A
/
Protocolos Clínicos
/
Análise Multivariada
/
Fatores de Risco
/
Ultrassonografia Doppler
/
Creatinina
/
Diabetes Mellitus
Tipo de estudo:
Estudo de etiologia
/
Guia de Prática Clínica
/
Estudo prognóstico
/
Fatores de risco
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Nephrology
Ano de publicação:
2010
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS