Effects of Quyu Xiaoban Capsule on vascular endothelial function in patients with atherosclerosis / 中国结合医学杂志
Chinese journal of integrative medicine
;
(12): 171-174, 2006.
Artigo
em Inglês
| WPRIM
| ID: wpr-314065
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the therapeutic effects of Quyu Xiaoban Capsule (QYXBC) on endothelial dependent vascular relaxation (EDVR) function in patients with atherosclerosis (AS) with ultrasonic technique.</p><p><b>METHODS</b>Tested were the endothelial function and blood lipids of 42 patients with AS in the treated group and 30 healthy volunteers in the control group. And re-examination of these parameters was carried out on the AS patients after they had been treated with QYXBC for 10 months.</p><p><b>RESULTS</b>Before treatment, the reactive hyperemia induced changes in artery diameter in the treated group was significantly lower than that in the control group (P < 0.01), while insignificant difference was found between the two groups in response to nitroglycerin. In the treated group after treatment, with D%-R improved significantly (P < 0.01), total cholesterol (TC), triglyceride (TG) and low-density lipoprotein cholesterol (LDL-C) decreased by 16.3%, 5.6%, 10.2% respectively and high-density lipoprotein cholesterol (HDL-C) increased by 7.5%. EDVR was correlated negatively with the serum TC, LDL-C concentrations and the baseline brachial diameter (D(0)) (r = -0.41, -0.66, -0.59, respectively, all P < 0.01), but correlated positively with HDL-C (r = 0.62, P < 0.05). The ameliorative extent of EDVR was correlated positively to the decreased magnitude of TC and LDL-C concentrations (r = 0.67, 0.59, both P < 0.01).</p><p><b>CONCLUSION</b>QYXBC can lower the level of blood lipids and improve significantly EDVR function.</p>
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DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Vasodilatação
/
Sangue
/
Artéria Braquial
/
Diagnóstico por Imagem
/
Medicamentos de Ervas Chinesas
/
Endotélio Vascular
/
Doenças das Artérias Carótidas
/
Ultrassonografia
/
Tratamento Farmacológico
Tipo de estudo:
Estudo diagnóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Chinese journal of integrative medicine
Ano de publicação:
2006
Tipo de documento:
Artigo
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