The long-term contrastive result of neo-urethra reconstructed with different kinds of tissue / 中华整形外科杂志

ABSTRACT

<p><b>OBJECTIVE</b>To observe the long-term apparent and structural change of the neo-urethra inner wall reconstructed with different kinds of tissue. To compare the difference between normal and reconstructed urethra for urethra reconstruction with more appropriate materials.</p><p><b>METHODS</b>The neo-urethra inner wall was observed during operation, through urography and urethroscope. The tissue section of neo-urethra inner wall was observed through light microscope and electron microscope.</p><p><b>RESULTS</b>With unchanged structure, the appearance of neo-urethra reconstructed with skin or mucosa could be close to normal urethra after a long time. Neo-urethra made of buccal mucosa possesses some of the most important basic structures for normal urethral microenvironment to form. The structure of neo-urethra made of bladder could be close to normal urethra after a long time.</p><p><b>CONCLUSIONS</b>Buccal and bladder mucosa may be a better material than skin for urethra reconstruction.</p>