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Analysis of risk factors of surgical site infections in breast cancer / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 559-562, 2010.
Artigo em Inglês | WPRIM | ID: wpr-314544
ABSTRACT
<p><b>BACKGROUND</b>Adjuvant chemotherapy has become an important component of standard therapy for breast cancer. However, until now, there have been few reports on the surgical site infections (SSI) after breast cancer surgery, specially after adjuvant chemotherapy. To study the risk factors of SSI of breast cancer, we analyzed patients diagnosed with breast cancer and treated with surgery.</p><p><b>METHODS</b>Fifty-five patients diagnosed with breast cancer and received breast conserving or modified radical operations in our hospital during January 2008 to March 2008 were selected. Factors (patients' age, body mass index (BMI), diabetes mellitus, no or administered adjuvant chemotherapy, with or without onset of myelosuppression and the degree, surgical approaches, duration of operation, postoperative drainage duration and total drainage volume) associated with SSI were retrospectively reviewed and statistically analyzed by single factor analysis.</p><p><b>RESULTS</b>Five patients suffered SSI (5/55, 9.1%); nineteen receiving adjuvant chemotherapy experienced Grade III + myelosuppression, among which 4 had SSI; only 1 out of the remaining 36 patients without adjuvant chemotherapy had SSI. The difference between the two groups was significant (P = 0.043). The incidence of SSI in patients with post-operative drainage tube indwelling longer than 10 days was 5/21, whereas no SSI occurred in that less than 10 days (P = 0.009). In our study, there was no significant difference in other associated factors.</p><p><b>CONCLUSIONS</b>Concurrent Grade III + myelosuppression after adjuvant chemotherapy is an important risk factor of SSI in breast cancer and needs further study. No SSI was detected with indwelling time of post operative drainage less than 10 days.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Cirurgia Geral / Infecção da Ferida Cirúrgica / Medula Óssea / Neoplasias da Mama / Estudos Retrospectivos / Fatores de Risco / Fator Estimulador de Colônias de Granulócitos / Quimioterapia Adjuvante Tipo de estudo: Estudo de etiologia / Estudo observacional / Fatores de risco Limite: Adulto / Idoso / Aged80 / Feminino / Humanos Idioma: Inglês Revista: Chinese Medical Journal Ano de publicação: 2010 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Cirurgia Geral / Infecção da Ferida Cirúrgica / Medula Óssea / Neoplasias da Mama / Estudos Retrospectivos / Fatores de Risco / Fator Estimulador de Colônias de Granulócitos / Quimioterapia Adjuvante Tipo de estudo: Estudo de etiologia / Estudo observacional / Fatores de risco Limite: Adulto / Idoso / Aged80 / Feminino / Humanos Idioma: Inglês Revista: Chinese Medical Journal Ano de publicação: 2010 Tipo de documento: Artigo