Sequential evaluation of brain lesions using functional magnetic resonance imaging in patients with Leigh syndrome / 南方医科大学学报
Journal of Southern Medical University
;
(12): 1474-1477, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-315438
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the value of functional magnetic resonance imaging (MRI) in sequential evaluation of patients with Leigh syndrome.</p><p><b>METHODS</b>Two patients with Leigh syndrome underwent diffusion weighted imaging (DWI), perfusion weighted imaging (PWI) and proton magnetic resonance spectroscopy ((1)H-MRS).</p><p><b>RESULTS</b>The brain lesions showed hyperintensity on DWI, lactate doublet peak on MRS and hyperperfusion in the patients at baseline, and maintained a hyperintensity on DWI and hyperperfusion in the absence of lactate doublet peak on MRS at follow-up 1 year later. DWI still revealed persistent hyperintensity in the brain lesions in one patient 2 years later.</p><p><b>CONCLUSION</b>Functional MRI can sensitively highlight the characteristics of brain lesions in patients with Leigh syndrome, and can therefore be used to evaluate the sequential changes of the brain lesions.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Encéfalo
/
Imageamento por Ressonância Magnética
/
Doença de Leigh
/
Métodos
Limite:
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS