Application of multi-coeffieient of variation significance test for toxicology study / 中华劳动卫生职业病杂志
Chinese Journal of Industrial Hygiene and Occupational Diseases
;
(12): 74-76, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-315689
ABSTRACT
<p><b>OBJECTIVE</b>To establish the methods of calculating and analyzing the multi-coefficient of variation significance test for the toxicology study.</p><p><b>METHODS</b>The paper aimed to confirm the significance level with the method of Bonferroni and then compared the methods of calculating and analyzing of the experiment groups with the control group respectively.</p><p><b>RESULTS</b>The significance level of multi-coefficient of variation significance test was confirmed as alpha1=0.0167. Compared with the control groups, the activity of ALT in serum both in 30 mg/kg and 60 mg/kg groups did not change in the average significance test, which was not statistically significant (P>0.05), while it changed in the variation significance test, which was of statistical significance (P<0.0167). The activity of AST in serum in 60 mg/kg group did not change in the average significance test (P>0.05), while it changed in the variation significance test (P<0.0167).</p><p><b>CONCLUSION</b>The complete changes of the indexes can only be shown by use of both the average significance test and the variation significance test together.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Aspartato Aminotransferases
/
Sangue
/
Distribuições Estatísticas
/
Ratos Wistar
/
Alanina Transaminase
/
Modelos Animais de Doenças
/
Intoxicação por Chumbo
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Industrial Hygiene and Occupational Diseases
Ano de publicação:
2009
Tipo de documento:
Artigo
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