Studies on HPLC fingerprint of cortex moutan / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To establish a HPLC fingerprint for quality evaluation of Cortex Moutan.</p><p><b>METHOD</b>The HPLC chromatographic fingerprinting of 30 lots of Cortex Moutan was established and major peaks were identified by LC-MS and MS-MS.</p><p><b>RESULT</b>The HPLC fingerprint of Cortex Moutan was established, showing 15 characteristic peaks. The areas of these peaks were found to complied with the following rule paeonol > 1, 2, 3, 4, 6-penta-O-galloyl-glucos > methyl gallate > galloylpaeoniflorin > gallic acid > oxypaeoniflorin > other compounds.</p><p><b>CONCLUSION</b>The chromatographic fingerprinting of Cortex Moutan with high specificity can be used to control its quality and monitor lot to lot consistency.</p>