The change trend of mother-to-child transmission rate of HIV-1 during 2005-2007 in some areas of China / 中华预防医学杂志
Chinese Journal of Preventive Medicine
;
(12): 984-987, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-316083
ABSTRACT
<p><b>OBJECTIVE</b>To explore the change trend of mother-to-child-transmission (MTCT) of HIV-1 in some areas in China.</p><p><b>METHODS</b>The investigation was conducted in 15 counties or districts of 4 provinces in China with relatively high HIV prevalence from January 2005 to June 2009. The data on the death and HIV-status of the babies born to HIV-positive mothers from January 2005-December 2007 in research sites were collected through 18-month following up after they were born.</p><p><b>RESULTS</b>During the time that the research was conducted, there were 644 babies born to HIV-positive mothers who were followed up for 18 months. At the end of 18 months, full data were collected from 550 babies, 44 babies were lost to follow-up and 50 babies died. Among 550 babies who were followed up for 18 months, 53 babies were confirmed as HIV positive. The rate of MTCT of HIV-1 was 13.19% (24/182), 8.90% (17/191) and 6.78% (12/177) in 2005, 2006, 2007 respectively, which showed a descending trend yearly (chi(2) = 4.23, P < 0.05). Adjusted by the death data of the HIV-exposed children, it was found that during 2005-2007 the rate of MTCT of HIV-1 was 16.74%, 12.98%, 9.52% respectively, which was also descending year by year (chi(2) = 4.69, P < 0.05).</p><p><b>CONCLUSION</b>Long-term, effective prevention of mother-to-child-transmission of HIV (PMTCT) could reduce the level of MTCT of HIV-1 year-by-year. In addition, using death data of HIV-exposed children to adjust the level of MTCT of HIV-1 is valuable to grade the effect of PMTCT.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
China
/
Mortalidade Infantil
/
Epidemiologia
/
Mortalidade
/
Síndrome da Imunodeficiência Adquirida
/
HIV-1
/
Transmissão Vertical de Doenças Infecciosas
/
Mães
Tipo de estudo:
Estudo prognóstico
Limite:
Feminino
/
Humanos
/
Lactente
/
Recém-Nascido
/
Gravidez
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Preventive Medicine
Ano de publicação:
2009
Tipo de documento:
Artigo
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