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The electrocardiographic changes in acute brain injury patients / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 3430-3433, 2012.
Artigo em Inglês | WPRIM | ID: wpr-316493
ABSTRACT
<p><b>BACKGROUND</b>Electrocardiographic (ECG) changes occurring during the course of acute brain injury (ABI) have been described frequently, but their significances remain uncertain. The present study was designed to investigate the relation of ECG abnormalities to outcome in the patients with ABI.</p><p><b>METHODS</b>We performed a retrospective, observational study on the ABI patients admitted to the Department of Neurosurgery of the Beijing Tiantan Hospital between December 2005 and December 2007. All the patients accepted 12-lead electrocardiographic examination within 24 hours after injury, then divided into three groups according to the Glasgow coma score (GCS). In-hospital mortality and one-month outcome assessed by the Glasgow outcome score (GOS) were investigated.</p><p><b>RESULTS</b>Of 335 ABI patients (mean ages 32.4 years), 246 patients (73.4%) had abnormal ECGs. The most common abnormality was ST-T changes (41.5%), followed by sinus tachycardia (23.6%). ECG changes had a significant association with the severity and outcome. Logistic regression analysis showed the presence of ST-T changes (OR 2.587, 95%CI 1.009 to 6.629, P = 0.048) and QT dispersion prolongation (OR 4.656, 95%CI 1.956 to 11.082, P = 0.001) significantly associated with short outcomes.</p><p><b>CONCLUSIONS</b>ABI can lead to myocardial damage and ECG changes had a significant association with the severity. ST-T changes and QT dispersion prolongation were the independent prognosis factors for the negative outcome of ABI patients.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Lesões Encefálicas / Modelos Logísticos / Estudos Retrospectivos / Eletrocardiografia Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adulto / Feminino / Humanos / Masculino Idioma: Inglês Revista: Chinese Medical Journal Ano de publicação: 2012 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Lesões Encefálicas / Modelos Logísticos / Estudos Retrospectivos / Eletrocardiografia Tipo de estudo: Estudo observacional / Estudo prognóstico / Fatores de risco Limite: Adulto / Feminino / Humanos / Masculino Idioma: Inglês Revista: Chinese Medical Journal Ano de publicação: 2012 Tipo de documento: Artigo