Study on antineoplastic effect of earthworm coelomic fluid in vitro / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
;
(6): 409-411, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-316887
ABSTRACT
<p><b>OBJECTIVE</b>To explore the antineoplastic effect in vitro of earthworm coelomic fluid (ECF)on growth inhibition and its mechanism for the tumor cell lines Siha, SW480, Colo205 and PC12.</p><p><b>METHODS</b>MTT colorimetric assay, flow cytometry and morphological analysis were used to test its antitumor activity on tumor cell lines and normal cell line Cos7 in vitro.</p><p><b>RESULTS</b>ECF can inhibit the cell growth of Siha, SW480, Colo205, PC12 and Cos7. But different tumor cell lines showed different sensitivity.</p><p><b>CONCLUSION</b>EFC can significantly inhibit the proliferation of tumor cells in vitro by inducing tumor cells apoptosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oligoquetos
/
Farmacologia
/
Líquidos Corporais
/
Linhagem Celular
/
Chlorocebus aethiops
/
Química
/
Células PC12
/
Apoptose
/
Células COS
/
Linhagem Celular Tumoral
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Experimental and Clinical Virology
Ano de publicação:
2010
Tipo de documento:
Artigo
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