Risk factors for fungal pneumonia in neonates: analysis of 160 cases / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 705-707, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-317352
ABSTRACT
<p><b>OBJECTIVE</b>To study the risk factors for the development of fungal pneumonia in neonates.</p><p><b>METHODS</b>A total of 260 neonates with nosocomial infectious pneumonia were classified into two groups fungal pneumonia (n=160) and bacterial pneumonia (n=100). Their medical data were retrospectively studied.</p><p><b>RESULTS</b>Eighty-seven percent of patients in the fungal pneumonia group had a duration of hospital stay of >10 days, but 30.1% of patients in the bacterial pneumonia group (p<0.01). The preterm infants in the fungal pneumonia group accounted for 49.5%, which was significantly higher than that in the bacterial pneumonia group (22.0%) (p<0.01). In the fungal pneumonia group, 59.9% of patients showed a weight of <2 500 g, but 34.0% of patients in the bacterial pneumonia group (p<0.01). The duration of the combined use of more than two broad-spectrum antibiotics (p<0.05) and the total duration of antibiotics use in the fungal pneumonia group was significantly longer than that in the bacterial pneumonia group (p<0.05). Nosocomial infectious bacterial pneumonia was common as the primary disease of fungal pneumonia (n=145).</p><p><b>CONCLUSIONS</b>Premature delivery, lower weight, longer duration of hospital stay and antibiotics use, and combined use of more than two broad-spectrum antibiotics may increase the risk of fungal pneumonia in neonates. The development of fungal pneumonia may be related to nosocomial infectious bacterial pneumonia in neonates.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pneumonia
/
Recém-Nascido Prematuro
/
Infecção Hospitalar
/
Estudos Retrospectivos
/
Fatores de Risco
/
Antibacterianos
/
Micoses
Tipo de estudo:
Estudo de etiologia
/
Estudo observacional
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2008
Tipo de documento:
Artigo
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