Evolutionary and transmission characteristics of rabies viruses in Asia / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To understand the rabies virus (RABV) evolutionary relationship between the strains of China and Asia and to know the evolution and transmission characteristics of RABV in Asia.</p><p><b>METHODS</b>The G sequences of representative strains from China were selected and combined the sequences of other countries in Asia to analyze using BEAST and MigraPhyla software.</p><p><b>RESULTS</b>The phylogenetic analysis showed that six groups (China I-VI) of China had different epidemic range China I , II and V groups just cycled in our country; China VI group, from Guangxi and Yunnan provinces, crossed with Southeast Asian strains; China III group and IV group also have closer genetic relationship with Asian country strains.</p><p><b>CONCLUSION</b>Geographic migration in Asia showed that Thailand and India may be two rabies transmission centers in Asia.</p>