Immobilization of CD34 antibodies onto ethylene-vinyl acetate copolymer coatings and in vitro cell attachments / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1130-1134, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-318199
ABSTRACT
Rapid re-endothelialization of implanted coronary artery stent is a new way for preventing restenosis. In this paper, adhesive polypeptide mimics of marine organism and antibodies potentially selective targeting with CD34 antigens on endothelial cells (ECs) were immobilized onto ethylene-vinyl acetate copolymer (EVA) coatings for improving the re-endothelialization process. The results showed that the attachments, growths, viabilities, as well as cell retentions of ECs on EVA were improved after modification. The immobilized polypeptide promoted the attachments of ECs, but overmuch polypeptide would restrict the attachments. With the increase of antibody concentration, the immobilized antibodies and cell attachments were improved.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Peptídeos
/
Polivinil
/
Veias Umbilicais
/
Adesão Celular
/
Stents
/
Células Cultivadas
/
Química
/
Antígenos CD34
/
Materiais Revestidos Biocompatíveis
/
Reestenose Coronária
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2008
Tipo de documento:
Artigo
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