Optimization of extraction process of Chrysanthemi Flos by multi-index orthogonal experiment / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 821-824, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-318637
ABSTRACT
<p><b>OBJECTIVE</b>To explore quantitative assessment indicators of Chrysanthemi Flos, and optimize the extraction process of Chrysanthemi Flos through orthogonal experimental design.</p><p><b>METHOD</b>The concentration of ethanol, amount of ethanol, extraction time and extraction frequency were selected as factors in the L9 (3(4)) orthogonal experiment. A comprehensive assessment was conducted with the peak area of the eight major common peaks in the fingerprint of Chrysanthemi Flos as the indicators.</p><p><b>RESULT</b>The optimum extraction process was selected as follows using ultrasonic extraction method, adding 30-fold ethanol with 80% concentration, extracting for 2 times for extraction, 40 min for each time.</p><p><b>CONCLUSION</b>The optimized extraction process is reliable, with controllable assessment indicators, which is significant to the standardization of the extraction process and quality control of Chrysanthemi Flos preparations.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Controle de Qualidade
/
Solubilidade
/
Fatores de Tempo
/
Medicamentos de Ervas Chinesas
/
Química
/
Reprodutibilidade dos Testes
/
Chrysanthemum
/
Etanol
/
Fracionamento Químico
/
Temperatura Alta
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2013
Tipo de documento:
Artigo
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