Leukemia stem cells and their microenvironment--editorial / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 1139-1141, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-318772
ABSTRACT
As pioneer of tumor stem cell research, leukemia stem cell research has not only important theoretical significance, but also clinical application potential. The survival and development of stem cells are directly impacted by their microenvironment. The research on leukemia stem cells and their microenvironment are now becoming a hot topic. The author presumes that stem cells are a population with heterogenecity and hierarchy; any single cell from the population is difficult to form a clone; the interaction between the leukemia stem cell and its microenvironment can be described by the concept of leukemia stem cell niche. In this article, the leukemia cell population with heterogenecity and hierarchy as well as leukemia stem cell niche were summarized and discussed.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Células-Tronco Neoplásicas
/
Leucemia
/
Células Estromais
/
Biologia Celular
/
Linhagem Celular Tumoral
/
Alergia e Imunologia
/
Nicho de Células-Tronco
/
Genética
/
Metabolismo
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2007
Tipo de documento:
Artigo
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