Expression of galectin-3 in invasive prolactinomas / 中国医学科学院学报

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the expression of galectin-3 (Gal-3) in prolactinomas.</p><p><b>METHODS</b>Expressions of Gal-3 were evaluated by immunohistochemistry using polyclonal antibody in 16 invasive prolactinomas and 16 prolactinomas.</p><p><b>RESULTS</b>Gal-3 was expressed both in invasive prolactinomas and noninvasive prolactinomas while significantly higher expression seen in the invasive prolactinomas (P < 0.05).</p><p><b>CONCLUSION</b>Gal-3 expression may be used as a useful indicator to determine the invasiveness and prognosis of prolactinomas.</p>