The correlation between neck lymphy node metastasis and matrixmetalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas / 华西口腔医学杂志
West China Journal of Stomatology
;
(6): 106-108, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-319046
ABSTRACT
<p><b>OBJECTIVE</b>To explore the correlation between neck lymph node metastasis and matrix metalloproteinase-2 expression at the invasive tumor front of oral squamous cell carcinomas(OSCC).</p><p><b>METHODS</b>Immunohistochemistry LsAB technique was used to observe the expression of MMP-2 at the invasive tumor front and center of OSCC, and the correlation between the expression of MMP-2 in OSCC and neck lymph node metastasis were respectively analyzed by statistics.</p><p><b>RESULTS</b>The results demonstrated that MMP-2 existed in all 71 cases, which the expression of MMP-2 at the OSCC front was more significant than that of MMP-2 at the OSCC center (P < 0.01), and related to neck lymph node metastasis (P < 0.05).</p><p><b>CONCLUSION</b>The expression of MMP-2 at the OSCC front could be considered as an index of judging the present of neck lymph node metastasis of OSCC.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Neoplasias Bucais
/
Imuno-Histoquímica
/
Carcinoma de Células Escamosas
/
Metaloproteinase 2 da Matriz
/
Linfonodos
/
Metástase Linfática
/
Invasividade Neoplásica
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
West China Journal of Stomatology
Ano de publicação:
2004
Tipo de documento:
Artigo
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