Prognostic Value of Erythrocyte Sedimentation Rate in Patients with Colorectal Cancer
Journal of the Korean Society of Coloproctology
;
: 351-356, 2008.
Artigo
em Coreano
| WPRIM
| ID: wpr-31929
ABSTRACT
PURPOSE:
Prognostic indicators are used increasingly in clinical trials and to guide surveillance for patients with colorectal cancer (CRC). The significance of a preoperative, elevated erythrocyte sedimentation rate (ESR) as a predictive indicator for malignancy and for prognosis in colorectal cancer has not been elucidated. Hence, the current study was conducted to evaluate the ESR as a prognostic indicator in patients with CRC.METHODS:
This study enrolled 232 patients who underwent surgery in our hospital between 1997 and 2004. ESR with clinicopathologic features and overall survival were evaluated retrospectively.RESULTS:
The ESRs of 139 patients were elevated, and those of 93 patients were normal. Elevated ESR was associated with the male gender, decreased hemoglobin, increased platelet count, high preoperative CEA, high preoperative CA19-9, tumor size (> or =5 cm), T stage, and TNM stage. Patients with elevated ESR had poorer survival (P=0.001), but a multivariate analysis did not reveal an elevated ESR as an independent factor for prognosis.CONCLUSIONS:
Preoperative elevation of ESR in patients with CRC suggests the presence of a tumor with aggressive behavior and a poor outcome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Contagem de Plaquetas
/
Prognóstico
/
Sedimentação Sanguínea
/
Hemoglobinas
/
Neoplasias Colorretais
/
Análise Multivariada
/
Estudos Retrospectivos
/
Eritrócitos
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
Journal of the Korean Society of Coloproctology
Ano de publicação:
2008
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS