Effect of taurine on thyroid hormone and second messenger in myocardium of rats after exhaustive exercise / 中国应用生理学杂志
Chinese Journal of Applied Physiology
; (6): 159-161, 2002.
Article
em Zh
| WPRIM
| ID: wpr-319349
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>AIM</b>Probe into protective action of taurine against exercise-induced myocardial damage in rats after exhaustive exercise.</p><p><b>METHODS</b>Using the model of exhaustive exercise, the present study researches into effects of taurine on the content of triiodothyronine (T3) and tetraiodothyronine (T4) in serum and myocardium as well as the activity of T(4) 5' deiodinase (T(4)5'-DI) and second messenger cAMP in myocardium of rats.</p><p><b>RESULTS</b>The content of T3 in serum and myocardium, T(4)5'-DI activity, second messenger cAMP in myocardium increased significantly (P < 0.01) while that of T4 in serum and myocardium did not change significantly after exhaustive swimming. The supplement of taurine might significantly inhibit above changes caused by exhaustive exercise.</p><p><b>CONCLUSION</b>Taurine could protect myocardium from exhaustive exercise induced damage by inhibiting hypermetabolism of thyroid hormone and change of second messenger.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Farmacologia
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Condicionamento Físico Animal
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Taurina
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Hormônios Tireóideos
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Sangue
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Sistemas do Segundo Mensageiro
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Ratos Sprague-Dawley
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Metabolismo
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Miocárdio
Limite:
Animals
Idioma:
Zh
Revista:
Chinese Journal of Applied Physiology
Ano de publicação:
2002
Tipo de documento:
Article