Insulin resistance model induced by dexamethasone in rats / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 98-100, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-319369
ABSTRACT
<p><b>AIM</b>To build a easy and reliable rat model of insulin resistance.</p><p><b>METHODS</b>Changes concerning sugar metabolism were observed in experimental rats injected intraperitoneally by different doses of dexamethasone.</p><p><b>RESULTS</b>The changes by dexamethasone in fasting blood insulin and insulin resistance prior to that of fasting blood glucose were dose and time dependent.</p><p><b>CONCLUSION</b>It was convenience to set up a insulin resistance model induced by dexamethasone in rats which would favor other related research.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Fisiologia
/
Fatores de Tempo
/
Sangue
/
Glicemia
/
Resistência à Insulina
/
Dexametasona
/
Ratos Sprague-Dawley
/
Modelos Animais de Doenças
/
Relação Dose-Resposta a Droga
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Applied Physiology
Ano de publicação:
2002
Tipo de documento:
Artigo
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