Expression of c-fos in various functional state of rat ovaries / 中国应用生理学杂志
Chinese Journal of Applied Physiology
;
(6): 88-92, 2002.
Artigo
em Chinês
| WPRIM
| ID: wpr-319371
ABSTRACT
<p><b>AIM AND METHODS</b>The method of labeled streptavidin biotin was used to study the expression of c-fos in various functional state of rat ovaries and its relationship with the levels of serum estradiol and progesterone.</p><p><b>RESULTS</b>(1) In the mature rat, c-fos expression was found higher in interstitial gland and stroma of proestrous ovaries and lower in estrous ovaries, and was found higher in luteal cells and stroma of pregnant ovaries and lower in diestrous ovaries. There was a positive correlation between the area and optical density of c-fos expression and the levels of serum E2 and P. (2) In the immature rats, c-fos expression was not found in the ovaries containing preantral follicles from DES-treated rats,and was found both in interstitial gland and stroma of the ovaries containing preovulatory follicles from PMSG-treated rats ,and the expression was higher in day 4 luteinized ovaries and lower in day 9 luteinized ovaries from PMSG with hCG treated rats. There also was a positive correlation between the area and optical density of c-fos expression and the levels of serum E2 and P.</p><p><b>CONCLUSION</b>The results suggested in rat ovaries and might play an important role in follicles development, ovulation, luteum formation and regression.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ovário
/
Fisiologia
/
Progesterona
/
Sangue
/
Regulação da Expressão Gênica
/
Proteínas Proto-Oncogênicas c-fos
/
Ratos Sprague-Dawley
/
Estradiol
/
Metabolismo
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Applied Physiology
Ano de publicação:
2002
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS