Research advances on associated genes and pathogenesis of hydrocephalus / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 644-649, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-319844
ABSTRACT
Hydrocephalus is a common medical condition characterized by abnormalities in the secretion,circulation or resorption of cerebrospinal fluid (CSF), resulting in ventricular dilatation. The pathogenetic mechanism for the hydrocephalus is attributed to the overproduction of CSF by the choroid plexus; the defect in CSF absorption and obstruction of CSF flow in the cerebral ventricles. However, the underlying etiology is poorly understood. With the development of genetic engineering, a growing body of evidence indicates that genetic factors play an essential role in the pathogenesis of hydrocephalus. It is the aim of this review to summarize these findings.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Ventrículos Cerebrais
/
Camundongos Knockout
/
Modelos Animais de Doenças
/
Genética
/
Hidrocefalia
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2010
Tipo de documento:
Artigo
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