A new indole derivative from endophyte Myrothecium roridum IFB-E091 in Artemisia annua / 药学学报
Acta Pharmaceutica Sinica
; (12): 1305-1308, 2015.
Article
em Zh
| WPRIM
| ID: wpr-320085
Biblioteca responsável:
WPRO
ABSTRACT
Three compounds were isolated from solid culture of endophyte Myrothecium roridum IFB-E091 in Artemisia annua. Their structures were determined as (S)-(-)-N-[2-(3-hydroxy-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-acetamide (1), N-(4-hydroxyphenethyl)acetamide (2) and asperfumoid (3), in which compound 1 was a new indole derivative. In cytotoxicity assay, the compound 1 had no obvious inhibition activity in human hepatoma cell line SMMC-7721 and human cervical carcinoma cell line HeLa.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Química
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Artemisia annua
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Linhagem Celular Tumoral
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Endófitos
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Hypocreales
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Indóis
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Microbiologia
Limite:
Humans
Idioma:
Zh
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2015
Tipo de documento:
Article