Effect of dachengqi granule on human gastrointestinal motility / 中国中西医结合杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the therapeutic effect and mechanism of Dachengqi granule (DCQG) on some digestive motility disturbed diseases.</p><p><b>METHODS</b>Gastroduodenojejunal manometry, electrogastrography (EGG), RIA of motilin and orocecal transit time test were applied to directly observe the effect of DCQG on human gastrointestinal motility.</p><p><b>RESULTS</b>DCQG could significantly improve the postoperational EGG disorder, elevate the amplitude and time of migrating motor complex (MMC) phase III, prevent gastrointestinal reversed peristalsis, increase the blood level of motilin, decrease the orocecal transit time, and promote the recovery of gastrointestinal motility.</p><p><b>CONCLUSION</b>DCQG is an effective digestive kinetic agent, which could be medicated conveniently in treating digestive motility disturbed diseases.</p>