An association study between the insertion/deletion polymorphism of angiotensin I converting enzyme gene and human speed endurance / 生物医学工程学杂志

ABSTRACT

This study was conducted to research the association between the insertion/deletion (I/D) polymorphism of Angiotensin I converting enzyme (ACE) gene and human speed endurance. Fourty subjects of Han nationality, healthy, with similar sports history were included. The I/D polymorphism of ACE gene was detected by polymerase chain reaction (PCR). The score of 800m run and the concentrations of the whole blood lactic acid were mensurated. Cluster analysis of the grade was made according to the result of cluster analysis. The subjects were divided into two groups high speed endurance group and low speed endurance group. We found that both the distributions of the ACE genotypes and the distributions of the ACE alleles there were no significant difference between high speed endurance group and low speed endurance group (P > 0.05); Whether at rest state, or after 800m run or the difference value between rest and after 800m run,the concentrations of the whole blood lactic acid did not exist significant difference among three kinds of genotypes groups (P > 0.05). There was on association with I/D polymorphism of ACE gene and human speed endurance.