Fusion of bone marrow-derived cells with cancer cells: metastasis as a secondary disease in cancer / 癌症
Chinese Journal of Cancer
;
(12): 133-139, 2014.
Artigo
em Inglês
| WPRIM
| ID: wpr-320529
ABSTRACT
This perspective article highlights the leukocyte-cancer cell hybrid theory as a mechanism for cancer metastasis. Beginning from the first proposal of the theory more than a century ago and continuing today with the first proof for this theory in a human cancer, the hybrid theory offers a unifying explanation for metastasis. In this scenario, leukocyte fusion with a cancer cell is a secondary disease superimposed upon the early tumor, giving birth to a new, malignant cell with a leukocyte-cancer cell hybrid epigenome.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Células-Tronco Neoplásicas
/
Células da Medula Óssea
/
Fusão Celular
/
Biologia Celular
/
Células Híbridas
/
Metástase Neoplásica
/
Neoplasias
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Chinese Journal of Cancer
Ano de publicação:
2014
Tipo de documento:
Artigo
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