Biological functions of decorin in cancer / 癌症
Chinese Journal of Cancer
;
(12): 266-269, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-320590
ABSTRACT
Decorin is a member of the extracellular matrix small leucine-rich proteoglycans family that exists and functions in stromal and epithelial cells. Accumulating evidence suggests that decorin affects the biology of various types of cancer by directly or indirectly targeting the signaling molecules involved in cell growth, survival, metastasis, and angiogenesis. More recent studies show that decorin plays important roles during tumor development and progression and is a potential cancer therapeutic agent. In this article, we summarize recent studies of decorin in cancer and discuss decorin's therapeutic and prognostic value.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Prognóstico
/
Biomarcadores Tumorais
/
Proliferação de Células
/
Matriz Extracelular
/
Decorina
/
Metabolismo
/
Metástase Neoplásica
/
Neoplasias
/
Neovascularização Patológica
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Journal of Cancer
Ano de publicação:
2013
Tipo de documento:
Artigo
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