Comparisons of efficacy of different pulmonary surfactants for the treatment of neonatal respiratory distress syndrome / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 253-255, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-320672
ABSTRACT
<p><b>OBJECTIVE</b>To compare the clinical efficacy of imported pulmonary surfactant (PS) pig lung phospholipids injection (pig PS) and domestic cattle lung surface-active agent (cattle PS) for the treatment of neonatal respiratory distress syndrome (NRDS).</p><p><b>METHODS</b>A total of 180 cases of grade IV NRDS receiving pig PS (n=90) or cattle PS treatment (n=90) were enrolled. The blood gas analysis and chest X-ray results and the incidence of complications after treatment, and hospitalization time and cost were compared between the two treatment groups.</p><p><b>RESULTS</b>The efficiency rate in the pig PS group (97%) was higher than in the catle PS group (83%) (P<0.01). The cure rate in the pig PS group was also higher than in the cattle PS group (84% vs 66%; P<0.01). The incidence of pneumothorax in the pig PS group was lower than in the cattle PS group (3% vs 7%; P<0.05). The hospitalization time in the pig PS group was shorter than in the cattle PS group (21 ± 4 days vs 23 ± 4 days; P<0.05). There were no significant differences in the total hospitalization cost between the two groups.</p><p><b>CONCLUSIONS</b>Pig PS seems to be superior to cattle PS in the treatment of grade IV NRDS.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Síndrome do Desconforto Respiratório do Recém-Nascido
/
Suínos
/
Gasometria
/
Surfactantes Pulmonares
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Economia
/
Hospitalização
/
Tempo de Internação
Tipo de estudo:
Avaliação Econômica em Saúde
Limite:
Animais
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS