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Morphological characteristics of submandibular glands of miniature pig / 中华医学杂志(英文版)
Chinese Medical Journal ; (24): 1368-1373, 2005.
Artigo em Inglês | WPRIM | ID: wpr-320767
ABSTRACT
<p><b>BACKGROUND</b>Miniature pig (minipig) is increasingly used as a large animal model for a variety of biomedical studies. Little information is available in the literature on anatomy, histology and sialograghy of the submandibular gland of the minipig. The purpose of this study was to characterize the morphology of a miniature pig's (minipig) submandibular gland as a large animal model for further biomedical studies.</p><p><b>METHODS</b>Five minipigs were subjected to sialographic, anatomic, histologic, histochemical and ultrastructural evaluations for submandibular glands.</p><p><b>RESULTS</b>Sialograms showed a long, horizontal main excretory duct and a pear-shaped gland located inferoposterior to the angle of the mandible. The submandibular glands lied superficial to the suprahyoid, and infrahyoid muscle groups, and were covered by the inferior portion of the parotid gland. The submandibular glands were characterized by a mixed parenchyma of mucous and serous secretory acini. Alcian blue (AB) staining and periodic acid-Schiff (PAS) reactions demonstrated that minipig submandibular glands synthesized and secreted acid mucous substances by serous cells and polysaccharide, and neutral mucous substances, by mucous cells.</p><p><b>CONCLUSION</b>The submandibular gland of the minipig is considered a useful large salivary gland animal model for biomedical studies.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fisiologia / Glândula Submandibular / Suínos / Porco Miniatura / Química / Biologia Celular / Histocitoquímica Tipo de estudo: Estudo prognóstico Limite: Animais Idioma: Inglês Revista: Chinese Medical Journal Ano de publicação: 2005 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Fisiologia / Glândula Submandibular / Suínos / Porco Miniatura / Química / Biologia Celular / Histocitoquímica Tipo de estudo: Estudo prognóstico Limite: Animais Idioma: Inglês Revista: Chinese Medical Journal Ano de publicação: 2005 Tipo de documento: Artigo