Effects of xihuangwan in assistant treatment of patients with advanced breast cancer / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1120-1123, 2014.
Article
em Zh
| WPRIM
| ID: wpr-321354
Biblioteca responsável:
WPRO
ABSTRACT
In order to explore the possibility of Xihuangwan (XHW)'s application in assistant therapy in patients with breast cancer, short- and long-term clinical efficacy were assessed in this study. Eighty and four patients with advanced breast cancer were selected in this study. They were divided into control group and treatment group randomly and evenly. All patients received surgical treatment followed by chemotherapy regimen composed of PTX + EPI + CTX (TEC regimen). Treatment group received additional assistant treatment of XHW. Short-term clinical efficacy was assessed by KPS, lesion stabilizing rate and side effects in 3-month follow-up study. Long-term clinical efficacy was assessed by overall survival (OS) and free-progression survival (FPS). KPS increased significantly after treatment in all patients (P < 0.05), more significantly in treatment group than in control group after treatment (P < 0.05); lesion stabilizing rate in treatment group increased significantly in treatment group than in control group (92.86% vs. 85.71%, P < 0.05); there was no significant difference between control group and treatment group in occurrence of side effects. Compared with control group, OS and FPS increased significantly in treatment group. Data in this study showed that XHW was suitable in treatment of advanced breast cancer due to its satisfactory short-term and long-term therapeutic effects.
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Índice:
WPRIM
Assunto principal:
Patologia
/
Fatores de Tempo
/
Neoplasias da Mama
/
Medicamentos de Ervas Chinesas
/
Estudos Retrospectivos
/
Seguimentos
/
Resultado do Tratamento
/
Intervalo Livre de Doença
/
Usos Terapêuticos
/
Tratamento Farmacológico
Tipo de estudo:
Observational_studies
/
Prognostic_studies
Limite:
Female
/
Humans
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2014
Tipo de documento:
Article