Effect and cost of perioperative use of antibiotics in coronary artery bypass grafting: a randomized controlled study / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 699-703, 2011.
Artigo
em Inglês
| WPRIM
| ID: wpr-321435
ABSTRACT
<p><b>BACKGROUND</b>Bacterial infections remain a serious complication following coronary artery bypass grafting (CABG). The objective of the study was to determine the effectiveness of a guideline for the appropriate use of antibiotics in CABG during the perioperative period.</p><p><b>METHODS</b>Six hundred and fourteen hospitalized patients who had undergone CABG from January to June 2006 were randomly allocated to an intervention group and a control group. The data on the hospital stay, days of antibiotic used, types of prophylactic antibiotics used, surgical wound infection and pulmonary infection and antibiotic costs for the patients were compared.</p><p><b>RESULTS</b>The postoperative hospitalization days of the intervention group were significantly fewer than that for the control group (P < 0.05). The time of antibiotic use and post-infection treatment time were also significantly less in the intervention group than in the control group (P < 0.05). The average hospital daily cost and total cost of antibiotics were less in the intervention group than in the control group (P < 0.05). Compared with the control group, prophylactic antibiotic use in the intervention group was more reasonable.</p><p><b>CONCLUSIONS</b>The guideline for the appropriate use of antibiotics in CABG during the perioperative period is effective strategies for reducing antibiotic costs, the time of antibiotic use and post-infection treatment time without compromising the patients' clinical outcome.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ponte de Artéria Coronária
/
Usos Terapêuticos
/
Economia
/
Período Perioperatório
/
Métodos
/
Antibacterianos
Tipo de estudo:
Ensaio Clínico Controlado
/
Guia de Prática Clínica
/
Avaliação Econômica em Saúde
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2011
Tipo de documento:
Artigo
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