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Evaluation for clinical staging parameters of prostate neoplasm / 中华男科学杂志
National Journal of Andrology ; (12): 100-102, 2003.
Artigo em Chinês | WPRIM | ID: wpr-322539
ABSTRACT
<p><b>OBJECTIVES</b>To evaluate significance of clinical parameters in prostate cancer staging.</p><p><b>METHODS</b>One hundred and twelve patients of prostate cancer were diagnosed by transrectal ultrasound-guided prostate needle biopsies. These cases were staged by pathologic diagnosis, MRI and bone scan. Clinical significance of serum PSA, Gleason score of biopsy, percentage of positive biopsy cores in prostate cancer staging were evaluated.</p><p><b>RESULTS</b>Of 112 patients, 30.4% (34/112) underwent radical retropubic prostatectomy. The serum PSA, Gleason score of biopsy and percentage of positive biopsy cores, were significant correlation with staging prostate cancer (r = 0.698, r = 0.674, r = 0.671, P < 0.001), and no significant difference between staging B and staging C (chi 2 = 2.675, P = 0.096; chi 2 = 0.704, P = 0.401). PSA in patients with stage D had significant difference with others (chi 2 = 5.135, P = 0.023; chi 2 = 4.593, P = 0.032). The sensitivity, specificity and accuracy of PSA were 76.7%, 50.0% and 71.4% respectively. Those of Gleason score and percentage of positive biopsy cores were 83.3%, 77.3%, 82.1% and 77.8%, 54.5%, 73.2% respectively.</p><p><b>CONCLUSIONS</b>The serum PSA, Gleason score of biopsy and percentage of positive biopsy cores had clinical significance in the staging of prostate cancer. Gleason score of biopsy in staging was more accurate than that of the other two parameters and the serum PSA can better predict prostate cancer metastasis.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Neoplasias da Próstata / Antígeno Prostático Específico / Métodos / Estadiamento de Neoplasias Tipo de estudo: Estudo prognóstico Limite: Idoso / Humanos / Masculino Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2003 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Patologia / Neoplasias da Próstata / Antígeno Prostático Específico / Métodos / Estadiamento de Neoplasias Tipo de estudo: Estudo prognóstico Limite: Idoso / Humanos / Masculino Idioma: Chinês Revista: National Journal of Andrology Ano de publicação: 2003 Tipo de documento: Artigo