Study on the serological diagnosis of Epstein-Barr virus among patients with mononucleosis / 中华流行病学杂志
Chinese Journal of Epidemiology
;
(12): 898-900, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-322900
ABSTRACT
<p><b>OBJECTIVE</b>To explore the relationship of Epstein-Barr virus (EBV) specific antibodies detection and the diagnoses of infectious mononucleosis (IM) caused by EBV.</p><p><b>METHODS</b>Single serum samples were collected from 220 inpatients with the diagnosis of IM between January 2005 and December 2006 in Beijing Children's hospital. The samples were detected for EBV-CA-IgM, EBV-CA-IgG, EBV-EA-IgG, EBV-NA-IgG and the avidity of EBV-CA-IgG by indirect immunofluorescent assay.</p><p><b>RESULTS</b>The positive rate of EBV-CA-IgG, EBV-CA-IgM, EBV-EA-IgG and EBV-NA-IgG were 100%, 95.9%, 79.5% and 4.1% respectively. Low-avidity EBV-CA-IgG was detected in 204 patients (92.7%) with positive EBV-CA-IgM and EBV-CA-IgG,negative EBV-NA-IgG, low-avidity EBV-CA-IgG were the main pattern of EBV antibody in IM patients (84.6%).</p><p><b>CONCLUSION</b>The existence of EBV specific antibody (CA-IgG, CA-IgM, EA-IgG, NA-IgG and avidity of CA-IgG) could add more information to identify the stage of EBV infection so as to provide more reliable serological evidence for the diagnosis of IM.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Virologia
/
Sangue
/
Imunoglobulina G
/
Herpesvirus Humano 4
/
Técnica Indireta de Fluorescência para Anticorpo
/
Infecções por Vírus Epstein-Barr
/
Diagnóstico
/
Alergia e Imunologia
/
Mononucleose Infecciosa
/
Anticorpos Antivirais
Tipo de estudo:
Estudo diagnóstico
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Lactente
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2007
Tipo de documento:
Artigo
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