Mass spectrometry technology and its application in analysis of biological samples / 药学学报
Acta Pharmaceutica Sinica
;
(12): 158-162, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-323065
ABSTRACT
With the excellent merits of wide analytical range, high sensitivity, small sample size, fast analysis speed, good repeatability, simple operation, low mobile phase consumption, as well as its capability of simultaneous isolation and identification, etc, mass spectrometry techniques have become widely used in the area of environmental science, energy chemical industry, biological medicine, and so on. This article reviews the application of mass spectrometry technology in biological sample analysis in the latest three years with the focus on the new applications in pharmacokinetics and bioequivalence, toxicokinetics, pharmacokinetic-pharmacodynamic, population pharmacokinetics, identification and fragmentation pathways of drugs and their metabolites and metabonomics to provide references for further study of biological sample analysis.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Espectrometria de Massas
/
Farmacocinética
/
Preparações Farmacêuticas
/
Equivalência Terapêutica
/
Química
/
Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos
/
Metabolômica
/
Métodos
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2012
Tipo de documento:
Artigo
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