Study on the progress of the mechanism of TGF-beta in the scarring and the effect of TCM / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 161-163, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-323115
ABSTRACT
Transforming growth factor (TGF-beta) plays a central role in wound healing and scarring. TGF-beta is a member of cytokine family, involving cell proliferation, migration, differentiation and apoptosis, which subsequently trigger extracellular matrix (ECM) deposite and collagen overproduction. A number of regulators of TGF-beta expression bave been identified, including Decorin CTGF, etc. TCM can reduced later scarring, and it accelerates wound healing. TCM can reduce the expression of TGF-beta, resistance of fibrosis, so that lighten the development of scar. This article reviewed the mechanism of TGF-beta in the scarring and TCM can decrease the development of scar effected by TGF-beta.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fibrose
/
Regulação da Expressão Gênica
/
Fator de Crescimento Transformador beta
/
Cicatriz
/
Tratamento Farmacológico
/
Medicina Tradicional Chinesa
/
Metabolismo
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
China Journal of Orthopaedics and Traumatology
Ano de publicação:
2008
Tipo de documento:
Artigo
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