Analysis of the factors related to glomerular filtration rate in type 2 diabetes without albuminuria / 南方医科大学学报
Journal of Southern Medical University
;
(12): 2502-2504, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-323623
ABSTRACT
<p><b>OBJECTIVE</b>To analyze the risk factors affecting the glomerular filtration rate (GFR) in type 2 diabetic patients without albuminuria.</p><p><b>METHODS</b>A total of 131 type 2 diabetic patients with normal urinary albumin excretion rate (UAER) were divided into normal GFR group and decreased GFR group. The factors relevant to GFR were analyzed by multiple factors regression.</p><p><b>RESULTS</b>Age, course of diabetes, systolic blood pressure, prevalence of hypertension, the level of serum creatinine (SCr), blood urea nitrogen (BUN) and uric acid (UA) were significantly higher in decreased GFR group than in normal GFR group. Multivariate regression showed that SCr, age, systolic blood pressure, and UA were negatively correlated to GFR.</p><p><b>CONCLUSION</b>Reduced GFR occurs in some type 2 diabetic patients without albuminuria. SCr, age, systolic blood pressure and UA are the major factors related to decreased GFR. The degree of early renal damage in diabetic patients can be better evaluated by combining GFR and UAER.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Epidemiologia
/
Prevalência
/
Fatores de Risco
/
Diabetes Mellitus Tipo 2
/
Nefropatias Diabéticas
/
Albuminúria
/
Taxa de Filtração Glomerular
/
Rim
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Fatores de risco
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2010
Tipo de documento:
Artigo
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