Comparative study of primordial germ cells in male and female mouse embryos / 南方医科大学学报
Journal of Southern Medical University
;
(12): 2175-2178, 2010.
Artigo
em Chinês
| WPRIM
| ID: wpr-323702
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the differences in the development of primordial germ cells (PGCs) between male and female mouse embryos.</p><p><b>METHODS</b>The morphological changes of genital ridge development were detected in C57BL/6J mouse embryos of 11-13.5 days, and the changes of PGCs quantity and proliferation were compared between the male and female embryos using immunofluorescence histochemistry.</p><p><b>RESULTS</b>The PGCs was the most numerous at 13.5 days in male and female embryos, and the quantity of proliferating PGCs reached the maximum at 13 days. The quantity of PGCs and proliferating PGCs in male embryos at 13 days was significantly larger than that in female embryos.</p><p><b>CONCLUSION</b>The development of PGCs is characterized by a gender differences in early development of mouse embryos (11-13.5 days).</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ovário
/
Testículo
/
Fatores Sexuais
/
Regulação da Expressão Gênica no Desenvolvimento
/
Biologia Celular
/
Proliferação de Células
/
Embrião de Mamíferos
/
Células Germinativas
/
Camundongos Endogâmicos C57BL
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Southern Medical University
Ano de publicação:
2010
Tipo de documento:
Artigo
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