Effects of immunotherapy with infantile recurrent respiratory tract infection by Chinese materia medica / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To explore the effect of Chinese materia medica on immune intervention of infantile recurrent respiratory tract infection.</p><p><b>METHOD</b>Thirty-one children of recurrent respiratory tract infection were randomly divided into two groups therapy group was treated with oral Chinese materia medica (b. i. d), control group was only treated with oral carboxymethyl liquor (< 4 years, 3 mL; 4-7 years, 5 mL; > 7 years, 7 mL, t. i. d). The change of IL-12,TNF-alpha, IL-6, IL-13, IL-6 and IL-4 in different time were observed and analyzes.</p><p><b>RESULT</b>Compared with the control group, the level of IL-12 and IL-2 was significantly increased after treatment of oral Chinese materia medica (P < 0.01), however, the level of TNF-alpha, IL-13, IL-4, and IL-6 was decreased after treatment (P < 0.01). During one years follow-up study, the frequency of respiratory infection every year of therapy group was significantly decreased than that of control group.</p><p><b>CONCLUSION</b>Chinese materia medica could prevent infantile recurrent respiratory tract infection effectively, increase humoral immunity function and ensure normal growth in children.</p>