Chemical constituents from dried sorophore of cultured Cordyceps militaris / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of the dried sorophore of cultured Cordyceps militaris.</p><p><b>METHOD</b>Compounds were isolated and purified by macroporous adsorption resin and silica gel column chromatography. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data (IR, FAB-MS, 1H-NMR and 13C-NMR).</p><p><b>RESULT</b>Nine compounds were isolated and identified as ergosta-4, 6, 8 (14)-tetraen-3-one (1), citrostadienol (2), tetracosanoic acid 2, 3-dihydroxypropyl ester (3), ergosterol (4), ergosterol peroxide (5), ergosta-7, 22-dien-3beta, 5alpha, 6beta-triol (6), cordycepin (7), adenosine (8), N-(2-hydroxyethyl) adenosine (9), respectively.</p><p><b>CONCLUSION</b>Compounds 1-3, 6, 9 were separated from the sorophore of cultured C. militaris for the first time.</p>